Is it permissible for him to lie to his parents in order to go out and seek (Islamic) knowledge?

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Check below answers in case you are looking for other related questions:
When seeking knowledge conflicts with honouring one’s parents
Can he tell lies to his parents in order to increase their good deeds?

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Related Answers:
How to seek knowledge
How can a seeker of knowledge make a schedule to organise his time?
Will he be sinning if he continues to use the computer although it is damaging his sight?
When seeking knowledge conflicts with honouring one’s parents
Can he tell lies to his parents in order to increase their good deeds?

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